Mineji Hayakawa Selected Research

Dacarbazine (DIC)

6/2022	Prognostic value of serum high mobility group box 1 protein and histone H3 levels in patients with disseminated intravascular coagulation: a multicenter prospective cohort study.
8/2021	Characterization of fibrin/fibrinogen degradation products reagents and their utility in critical care patients with enhanced fibrinolysis.
7/2020	The Association Between Sequential Organ Failure Assessment Scores and Mortality in Patients With Sepsis During the First Week: The JSEPTIC DIC Study.
2/2019	External Validation of the Two Newly Proposed Criteria for Assessing Coagulopathy in Sepsis.
1/2019	Optimal Timing and Early Intervention With Anticoagulant Therapy for Sepsis-Induced Disseminated Intravascular Coagulation.
1/2019	Changes in Mannose-Binding Lectin and Collectin Kidney 1 Levels in Sepsis Patients With and Without Disseminated Intravascular Coagulation.
1/2019	The Treatment Intensity of Anticoagulant Therapy for Patients With Sepsis-Induced Disseminated Intravascular Coagulation and Outcomes: A Multicenter Cohort Study.
1/2019	Epidemiology of disseminated intravascular coagulation in sepsis and validation of scoring systems.
12/2018	Nationwide registry of sepsis patients in Japan focused on disseminated intravascular coagulation 2011-2013.
9/2018	Optimal Antithrombin Activity Threshold for Initiating Antithrombin Supplementation in Patients With Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter Retrospective Observational Study.

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Mineji Hayakawa Research Topics

Disease

46	Disseminated Intravascular Coagulation 06/2022 - 01/2003
36	Sepsis (Septicemia) 01/2022 - 08/2002
22	Wounds and Injuries (Trauma) 01/2022 - 12/2002
14	Thrombosis (Thrombus) 06/2022 - 12/2002
13	Hemorrhage 03/2021 - 11/2009
12	Septic Shock (Toxic Shock Syndrome) 01/2021 - 08/2002
11	Multiple Organ Failure (MODS) 01/2016 - 08/2002
10	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 08/2017 - 08/2002
8	Critical Illness (Critically Ill) 02/2022 - 07/2006
8	Out-of-Hospital Cardiac Arrest 08/2021 - 05/2008
7	Shock 12/2020 - 05/2009
6	Heart Arrest (Cardiac Arrest) 10/2021 - 05/2008
6	Inflammation (Inflammations) 07/2013 - 12/2002
4	Hypothermia 01/2022 - 03/2016
2	Lung Injury 01/2022 - 01/2010
2	COVID-19 01/2022 - 08/2021
2	Respiratory Insufficiency (Respiratory Failure) 01/2019 - 10/2017
2	Hypotension (Low Blood Pressure) 08/2017 - 03/2016
2	Acidosis 09/2016 - 03/2016
2	Body Weight (Weight, Body) 01/2015 - 12/2008
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2010 - 01/2003
1	AIDS-Related Complex (ARC) 02/2022
1	Ventilator-Induced Lung Injury 01/2022
1	Thrombocytopenia (Thrombopenia) 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Chronic Renal Insufficiency 08/2021
1	Post-Cardiac Arrest Syndrome 08/2021
1	Heart Diseases (Heart Disease) 12/2020
1	Hyperkalemia 10/2019
1	Reperfusion Injury 10/2019
1	Cardiac Arrhythmias (Arrythmia) 10/2019
1	Traumatic Brain Injuries (Traumatic Brain Injury) 08/2017

Drug/Important Bio-Agent (IBA)

47	Dacarbazine (DIC)FDA LinkGeneric 06/2022 - 08/2002
14	ThrombomodulinIBA 01/2022 - 12/2002
12	AntithrombinsIBA 09/2018 - 12/2006
11	Fibrinogen (Factor I)FDA Link 03/2021 - 12/2006
10	AnticoagulantsIBA 02/2019 - 06/2012
10	Leukocyte Elastase (Neutrophil Elastase)IBA 12/2012 - 08/2002
8	FibrinIBA 09/2016 - 01/2007
6	formycin diphosphate (FDP)IBA 08/2021 - 01/2007
6	fibrin fragment D (D-dimer)IBA 01/2021 - 01/2007
5	Plasminogen Activators (Plasminogen Activator)IBA 10/2021 - 01/2007
5	Fibrin Fibrinogen Degradation ProductsIBA 08/2021 - 01/2007
5	Thromboplastin (Tissue Factor)IBA 07/2013 - 08/2002
4	Hemostatics (Antihemorrhagics)IBA 01/2022 - 07/2011
4	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2020 - 11/2009
3	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2021 - 02/2011
3	Protein CIBA 01/2016 - 01/2007
3	Thrombin FDA Link 03/2015 - 07/2011
3	Fibrinolysin FDA Link 12/2012 - 01/2007
3	Antithrombin IIIIBA 10/2009 - 12/2006
2	CreatinineIBA 02/2022 - 01/2015
2	Heparin (Liquaemin)FDA LinkGeneric 01/2022 - 01/2016
2	Plasminogen Activator Inhibitor 1IBA 10/2021 - 01/2007
2	Lactic Acid (Lactate)FDA LinkGeneric 08/2017 - 02/2011
2	Blood Coagulation Factors (Coagulation Factor)IBA 01/2017 - 07/2011
2	Intravenous Immunoglobulins (IVIG)FDA Link 01/2017 - 06/2010
2	Indicators and Reagents (Reagents)IBA 09/2016 - 03/2016
2	Epinephrine (Adrenaline)FDA LinkGeneric 01/2015 - 01/2013
2	estropipate (Ogen)FDA LinkGeneric 07/2013 - 07/2011
2	Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)IBA 12/2012 - 02/2011
2	Macrophage Migration-Inhibitory FactorsIBA 06/2011 - 08/2007
2	urinastatin (MR 20)IBA 05/2008 - 01/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2008 - 08/2007
2	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2005 - 12/2002
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2005 - 12/2002
2	SelectinsIBA 01/2005 - 12/2002
2	lipoprotein-associated coagulation inhibitor (TFPI)IBA 01/2003 - 08/2002
1	HMGB1 Protein (HMG1)IBA 06/2022
1	Histones (Histone)IBA 06/2022
1	Proteins (Proteins, Gene)FDA Link 06/2022
1	Vancomycin FDA LinkGeneric 02/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	Platelet Factor 4IBA 01/2022
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2022
1	AntibodiesIBA 01/2022
1	IceIBA 10/2021
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2021
1	Vasopressins (Vasopressin)IBA 01/2021
1	Plasminogen InactivatorsIBA 01/2020
1	PlasminogenIBA 01/2020
1	ImmunosorbentsIBA 01/2019
1	Collectins (Collectin)IBA 01/2019
1	Complement System Proteins (Complement)IBA 01/2019
1	EnzymesIBA 01/2019
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2019
1	Polymyxin B (Aerosporin)FDA LinkGeneric 06/2017

Therapy/Procedure

11	Therapeutics 01/2022 - 01/2016
6	Cardiopulmonary Resuscitation (CPR) 08/2021 - 05/2009
5	Critical Care (Surgical Intensive Care) 10/2021 - 04/2015
2	Rewarming 01/2022 - 10/2021
2	Artificial Respiration (Mechanical Ventilation) 01/2022 - 08/2013
2	Extracorporeal Membrane Oxygenation 10/2021 - 10/2017
2	Resuscitation 08/2021 - 03/2016
2	Continuous Renal Replacement Therapy 05/2009 - 07/2006
1	Induced Hypothermia 08/2021
1	Blood Transfusion (Blood Transfusions) 03/2021
1	Renal Dialysis (Hemodialysis) 12/2020
1	Hemoperfusion 06/2017